Myawaddy is a moderately popular destination for tourists and expats in Thailand who want to make a "visa run" (i.e. get a new Thai entry permit stamp by making a short visit to another country).
Foreigners are not as yet allowed to travel further overland into Myanmar from Myawaddy - their only option is to go back across the border to Mae Sot before the border closes at 18:00 (foreigners are not permitted to stay in Myawaddy overnight).
There are several buses daily from Myawaddy to Hpa-an (Pa-an) and Mawlamyine (Moulmein), however a Myanmar or Thai passport or ID card is required.
The road west from Myawaddy to Kawkareik and beyond is being significantly upgraded and at some time in the future the Mae Sot - Myawaddy border crossing will probably become the main overland entry point for foreign travellers wishing to get from Bangkok to Yangon (and vice-versa) overland.
The time in Myawaddy is 30 minutes earlier than in Mae Sot, and the traffic (mostly) drives on the right.
From the Thai town of Mae Sot, take a songthaew or other transport to the border crossing at the Thai-Myanmar Friendship Bridge over the Moei River; Myawaddy is immediately on the other side of the bridge.
Foreigners must deposit their passports at the Myanmar immigration checkpoint and pay a USD10 fee for a one-day entry permit. This fee should be paid with pristine USD notes; if paid in Thai currency, the fee is appreciably higher (typically 500 baht). No fees are payable at the Thai checkpoint. Normal exit and entry stamps are issued at both checkpoints.
Foreigners can only cross the border into Myanmar at this point on foot (unusually, foreigners are not permitted to cross with bicycles).
Myawaddy is centered around the wide strip of highway that leads from the Friendship Bridge through town, and is small enough to easily be explored on foot; alternatively, ubiquitous red bicycle rickshaws go everywhere.
There are several guesthouses and small hotels, however foreigners are not permitted to stay in Myawaddy overnight.