Uptown is in Houston, though nobody in Houston has used that term since about 1970 --- it's generally referred to as "The Galleria", or to motorists at I-610 and U.S. 59 as the highway to avoid.
- Williams Tower, 2800 Post Oak, . The 3rd largest skyscraper in Houston and largest in the world outside of a downtown or central business district. A short walk from the Galleria, also check out the ever-romantic Water Wall.
- St. Arnolds Brewery, 2000 Lyons Ave., . Weekdays: 3PM, Saturday: 11AM. Houstonians looking for a fun Saturday afternoon head to Saint Arnolds at 11AM when they do their weekly brewery tour and open up the taps for the thirsty locals. Great local vibe! Weekday tours are offered at 3PM. $7.00 per person (includes tasting glass).
- Memorial Park. Located just inside the I-610 Loop along Memorial Drive, this expansive slice of urban greenspace has some wonderful trails and paved paths, good for jogging, rollerblading, and bicycling. There's an arboretum, a nature center, picnic areas, and sports fields. This is one of Houston's nicest parks.
- The Galleria, Westheimer at Post Oak, . Huge shopping mall filled with high end retail stores and restaurants, several hotels and even includes an indoor year-round ice skating rink used by Tara Lipinski. Free parking (if you find the right lots).
- Marq*E, . Outdoor shopping mall with many attractions including a giant movie theater.
- River Oaks District, 4400 Post Oak Parkway, Ste 1460, . Outdoor mixed use development featuring many upscale shops such as Cartier, Dior, Dolce & Gabbana, Hermes, etc.
- America's Restaurant, 1800 Post Oak Blvd, . The menu draws from the foods and cooking techniques of North, Central and South America, to make one New World Cuisine; as you pass under its Mayan-inspired door, you quickly realize that nothing about this place is ordinary.
- Argentina Cafe, 3055 Sage Road,, ☎ (713) 622-8877, . Restaurant specializing in Argentinean fare. Be sure to try their empanadas.
- Cafe Annie, 1728 Post Oak Blvd, ☎ 713-840-1111, . Insanely expensive prices, but very good American cuisine. Reservations required.
- Caracol, 2200 Post Oak Blvd Ste 160, ☎ 713-622-9996, . Restaurant serving upscale Mexican cuisine specializing in fare from Mexico's sixteen coastal states. Reservations required.
- Chacho’s Mexican Restaurant, 6006 Westheimer Rd, ☎ 713-975-9699, . Mexican take out joint that is open 24 hours.
- Ekko’s Greek American Deli, 5216 Richmond Ave, ☎ 713-626-5263, . Located inside a gas station, this restaurant serves burgers, sandwiches, and many greek specialties such as gyros, mousaka, and souvlaki.
- Kenny & Ziggy's Deli, 2327 Post Oak Blvd, ☎ 713-871-883, . One of the few authentic New York style deli's in Houston, and was featured on Guy Fieri's Diners, Drive-In's, and Dives.
- Mary’z Lebanese Cuisine, 5825 Richmond Ave, ☎ 832-251-1955, . Restaurant featuring Lebanese and Middle Eastern cuisine. They also have a hookah lounge too.
- Mystery Cafe, 2400 West Loop South (Sheraton, IH-610 at Westheimer), ☎ 713-944-2583, . "Where MURDER is always on the menu!" $52.95/person.
- Ragin' Cajun, 4302 Richmond Ave., ☎ 713-623-6321. This is the world's best cajun kitchen that hasn't been destroyed by a hurricane. Gumbo, jambalaya, and crawdads are served up in a funky, downhome casual restaurant where the zydeco music never stops.
- The Tasting Room, 1101 Uptown Park Blvd, ☎ 1.713.993.9800. With more seating then any other bar in Houston, the Tasting Room is a unique experience and is an ideal spot for a great night out. Choose from over 200 wines priced from the reasonable $15 per bottle to the indulgent $1,000 per bottle.
- Wild West, 6101 Richmond Ave, Houston,, ☎ (713) 266-3455.
- Aloft Houston Galleria, 5415 Westheimer Road, ☎ 713-622-7010, . A hotel very popular with business travelers that located just blocks away from the Galleria.
- Courtyard - Galleria, 3131 West Loop S, .
- Fairfield Inn - Galleria, 3131 West Loop S, . A quarter of a mile from uptown, near Houston's Galleria Mall.
- Hotel Indigo, 5160 Hidalgo St Houston, TX 77056, .
- Houston Marriott Westchase, 2900 Briarpark Dr.,  This Houston Westchase hotel is located just minutes from the Uptown/Galleria Area for some of the country's finest shopping and dining.
- Houston Marriott West Loop by The Galleria, 1750 West Loop South, . The Houston Marriott West Loop by The Galleria is located just blocks from the Uptown Park and Galleria shopping areas.
- Hyatt Summerfield Suites, 3440 Sage Road, . Pet-friendly, all-suite hotel near Houston Galleria Mall
- Royal Sonesta Hotel Houston, 2222 West Loop South Freeway, ☎ 7136277600, . Located in the heart of Uptown Houston near The Galleria, this hotel offers spacious accommodations, meeting space, vacation packages and easy access to the Museum and Theater districts.
- Red Roof Inn Houston-Westchase, 2960 West Sam Houston Parkway South, ☎ 832-301-3700, . Welcome to Red Roof Inn Houston-Westchase a family-friendly and pet-friendly hotel in Houston located on the Sam Houston Parkway.
- Granduca Houston, 1080 Uptown Park Boulevard, (888) 472-6382, . Houston's newest luxury hotel offers the ambiance of an Italian palace along with the upscale touches of a five-star hotel.
- Hotel Derek, 2525 W. Loop South, (713) 961-3000, . One block from the world-renowned Houston Galleria shopping and dining.
- The Houstonian, 111 North Post Oak Lane, Tel. (713) 680-2626, . Located on a wooded 18-acre site, the hotel includes a fitness club and full-service spa.
- InterContinental Houston, 2222 W. Loop South, (713) 627-7600, . One block from the world-renowned Houston Galleria shopping and dining.
- Omni Houston Hotel, 4 Riverway, ☎ +1 (713) 871-8181, . The Omni Houston Hotel is centrally located in the prestigious Uptown Post Oak/Galleria area and is just minutes from all of the excitement that Houston, Texas has to offer.