The largest airport in the region is the Mihail Kogălniceanu International Airport , not so conveniently located some 25 km north-west of Constanta. Usually, Carpatair  flies three times per week from Timisoara, Tarom  flies once weekly from Bucharest and Istanbul, but in summer there are also weekly flights to and from Budapest, Düsseldorf, Frankfurt, Ljubljana, Strasbourg, Minsk, Oslo and also from major cities in Romania.
There are 7 - 8 daily trains from Bucharest to Constanta (note that many of them leave from Bucharest's Obor train station, not from Gara de Nord). In summer there are direct trains to Constanta from most regions in Romania ( from cities like Cluj, Oradea, Brasov, Timisoara, Iasi etc).
The only direct train from Bucharest to Tulcea leaves from Bucharest Obor train station.
Check train timetables on infofer.ro.
The partially completed Bucharest - Constanta motorway has considerably improved travel times by car to this region.
Buses and minibuses from Bucharest to Constanta and the Black Sea resorts are very frequent; check autogari.ro for timetables. There are also buses from Istanbul to Constanta.