Umbertide lies on the River Tiber, the river that eventually passes through Rome. Unlike most Umbrian cities, which are hill towns, it lies on flat land. It is an important industrial center producing machine tools, farm machinery, ceramics and other products. Compared with other cities in the region it also has relatively little history, with its formation dating back to around the 10th Century. Its original name was Fratta and for much of its history it has been under the control of Perugia. It received its present name in 1863 in honor of the then Crown Prince Umberto. Most of its attractions are also relatively recent.
On April 25th, 1944 Allied planes mistakenly dropped bombs on the medieval part of the town, causing considerable damage and killing sixty people.
There are train connections via Perugia.