Teplice (German: Teplitz) is a city in Bohemia, Czech Republic. Teplice is known for its thermal spas, which are particularly popular with visitors from the Middle East. The town used to be one of the most prestigious spas in the world and hosted famous persons such as Ludwig Van Beethoven.
You can use daily direct train connections from Prague main station or Holešovice station. Price for one-way ticket is approximately 150 CZK (~7 EUR). Train comes nearly every hour during working days. You can visit Usti nad Labem city center on the way as the train stops in the main station situated there, train connections to Teplice from Usti are even more frequent. Buses from Prague are also available and cheaper, however not nearly as comfortable.