===Gay and lesbian===
Homosexuality is legal between consenting adults in all states as of 2003, and same-sex marriage was legalized in all states in 2015. Some states and cities have anti-discrimination codes, including public accommodations in hotels, restaurants and transportation and some states don't have it.
Some Americans take a live-and-let-live approach to sexuality, but there are significant exceptions. It can be a problem to be open about one's sexual orientation and some places you will receive unwanted attention, remarks, threats, violent attacks, be physically attacked with police unsympathetic to your need for help or complicit, and be refused service. A significant amount of this occurs in [[Texas]], [[Wyoming]], the [[Midwest]] and the [https://wikitravel.org/en/South_(United_States_of_America) '''South''']. Attitudes toward homosexuality vary widely in regions with a reputation for tolerance. Tolerance is in some major cities throughout the country specifically around the Pacific Coast, some parts of the [[Northeast]] and [[Hawaii]]. Gay-friendly destinations include [[New York City|New York]]'s [[Manhattan/Chelsea Garment District|Chelsea]], [[Rochester]] in Western [[New York State]], [[Cape Cod]] in [[Massachusetts]], [[Chicago]]'s [[Chicago/Lakeview-North Center|Boystown]], [[Seattle]]'s [[Seattle/Capitol Hill-Central District|Capitol Hill]], [[San Francisco]]'s [[San Francisco/Castro-Noe Valley|Castro Street]], [[Washington, D.C.|Washington]]'s [[Washington (D.C.)/Dupont Circle|Dupont Circle]], [[Miami Beach]]'s [[Miami/South Beach|South Beach]], [[Atlanta]]'s [[Atlanta/Midtown|Midtown]] and [[Los Angeles]]' [[West Hollywood]]. [[Massachusetts]] is usually tolerant. An increasing number of resort areas are known as gay-friendly, including [[Fire Island]], [[Key West]], [[Asheville]], [[Provincetown]], [[Ogunquit]], [[Rehoboth Beach]], [[Saugatuck-Douglas|Saugatuck]], and parts of [[Asbury Park]]. In a few smaller cities, there are neighborhoods where gay people tend to congregate and have resource centers for LGBT people. Some gay-friendly businesses like to advertise themselves as such with a rainbow flag or a small pink triangle or three-vertical-striped sticker in the window. Men planning to engage in any sex, should be aware the heightened risk of HIV and other infections in the United States. A gay American man is 44 times more likely to contract HIV than a heterosexual one, and 46 times more likely to contract syphilis. This risk grows greatly among men likely to engage in one-night stands and other higher-risk behavior. In a nation where 0.5% of the population are infected with HIV, unprotected sex is a very real risk. '''Precautions, including safer sex, are strongly advised during your stay.''' Most cities have affordable or free testing and treatment centers for STIs at least for gay men, though hours may be limited and waits may be long. Lesbians and trans face the same risk. The life-long repercussions of HIV or other STIs aren't covered by healthcare providers and seeking health care elsewhere can be very pricey.
Street drugs, including but not limited to cocaine, heroin, and methamphetamines, are illegal under federal law throughout the US.