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* '''Interstate 90 (I-90) / WA-17 ''' Going west on I-90 from Spokane, Ephrata is accessed from Exit 179 (S Pioneer WA-17). Go another 0.8mi along Pioneer Way
* '''Interstate 90 (I-90) / WA-283''' Going east on I-90, from Seattle, Ephrata is accessed from Exit #151 (Ephrata/Soap Lake). Go NE along WA-283 for the next 20mi/32km to get into Ephrata. WA-283 goes through town as Basin St.