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[[Baltimore/West Baltimore|West Baltimore]] is where it all begins, right on Lexington and Fulton Ave where '''Snot Boogie''', the man of unfortunate name and unfortunate life lay dead in the street. While nearly the whole of the drug gang plotlines theoretically take place in West Baltimore, only the first season was extensively shot here. The directors found East Baltimore's relatively treeless streets much easier to film in, as they could film throughout at least three of the seasons without losing seasonal continuity. To reach the series opening scene, ''head up MLK Jr Ave, turn left onto W Fayette St, then after going a ways, right on Fulton Ave and up two blocks to Lexington''. The scene was filmed on Lexington on the block just to the left. As you drive through West Baltimore, keep a lookout for the famous '''horse cart fruit vendor''' in good weather—he's very much real, and quite the living legend.
''Turn right on Lexington and turn right onto Mount St. Go about four blocks'' and look for the '''Viva House''' (44 S Mount St) soon after crossing Hollins St, where Bubbles cooked and served at the '''soup kitchen'''. ''Turn left on Lombard and left again onto Gilmor St to get back to Lexington St.'' You will pass by beautiful Union Square on the right, with the HL Mencken Fountain in the center. Mencken, the "Sage of Baltimore" lived
''Turn right on Lexington to go back east towards MLK Jr Blvd.'' Once you reach Amity St, look left—the second building on the right is the famous '''Poe House'''. In the show, a lost tourist asks a local kid where the Poe House is. The local accent pronounces Poe and poor the same way, so the perplexed boy responds, "uh, take your pick!" Fortunately, you brought your Wikitravel map, so you won't have to reenact this silly scene. While closed for winter, the house of Edgar Allen is open for a small fee and tour from April to early December, Th-Sa noon-3:30PM. Just go up to the front door and knock. Street parking right on Lexington couldn't be easier.