Orillia is a city in Ontario.
Orillia is located approximately 1.5 hours north of Toronto and is located on Ontario Highway 11/12 via Highway 400 North.
Ontario Northland  has regular service from Toronto. Check their website for details.
The Orillia Transit System provides service throughout the City of Orillia, with buses operating on four routes. Buses leave downtown every half hour, some alternating, during the following hours. Mon - Fri - 6:15 am to 6:15 pm and Saturday - 8:45 am to 5:45 pm.
Orillia is a good central location to start with if travelling back and forth to several locations in Southern Ontario. Muskoka, including Gravenhurst, Huntsville, and Parry Sound is nearby to the north continuing up to North Bay and Sudbury. To the south down Highway 400 is Barrie, and Toronto. A few hours along highway 7 to the east is Ottawa.