Many of the ideas in Frank Herbert's Dune series came to him during a trip to Florence to write a magazine article about a US Department of Agriculture project there.
Florence is also known as the site of the exploding whale, an incident when the Oregon State Highway Division tried to remove a beached whale by dynamite - with unintended results.
Florence Municipal Airport has general aviation services but no scheduled flights
Porter Stage Lines  run a twice-daily service from Ontario (Oregon) to Coos Bay, which calls at Florence. It connects in Eugene with Greyhound bus and Amtrak train services. Through ticketing is available.
The scenic Oregon coast route, US Highway 101, passes through Florence. The Eugene-Florence Highway, Oregon route 126, follows the Suislaw River valley to dead-end on 101 at Florence.
Go Kart/Bumper Boats/Mini golf are also available at Sandland Adventures.
Flashback Old Time Photos: Dress up in Old West style for a photo session. Located in Old Town, 175 Nopal St, (541) 997-1686. (Closed Mondays)
Skateboard: Skaters from up and down the coast come to enjoy Florence's skate park, located at Miller Park
Honeyman State Park: South of town on Highway 101, Cleowox Lake has a swimming area buffered by a tall sand dune, fun for running down, or riding a sand board. This is one of the biggest campgrounds in the state (tent sites, electric, full hookups, yurts), reservations are imperative in summer.
Sand board at Sand Master Park
Florence Old Town is full of shops selling coastal art, clothing, gourmet food, and other goodies.
Funky Monkey Toys located on Bay Street is an excellent high-quality toy shop.
Antique shops off Highway 101 on the south side of town (not too far from the bridge)
Sportsman (west side of Highway 101) sells all matter of outdoor gear as well as hunting and fishing licenses.
Recreational marijuana dispensaries available in town and just south of Florence.
Restaurants are clustered in the old town, especially in Bay Street; those on the river side of the street usually have decks over the river.
The Waterfront Depot in Bay Street, with a river deck, is the restaurant most strongly recommended by locals, and reservation is advised. It is housed in the former railroad depot from Mapleton, a few miles up the Suislaw River. The Italian restaurant (1285 Resto Bar) opposite the Waterfront Depot is under the same ownership and is also strongly recommended by locals.
Mo's - Fish & Clamchowder restaurant in Florence's old town. Great view of the Siuslaw river and one of the best clam chowders to be found on the Oregon coast. This local chain of restaurant's was started in Newport, Oregon.
Maple Street Grille - In Old Town, but not on the main drag so tourist often miss this local favorite: great cocktails and delicious New American cuisine
Big Dog Donuts & Deli - east side of Highway 101. Incredible, fresh donuts and big juicy sandwiches (pastrami, ruben, etc.)
Taste of Hawaii - A yellow food truck usually set up on the east side of Highway 101. Owner is from Hawaii and makes hearty plate lunches of kahlua pork and teriyaki chicken, as well as generously portioned creative sushi rolls (not open Mondays)
Rosa's - Homey Mexican food on the north end of town. Great service and delicious fresh salsa
Old Town Florence packs many more great restaurants, many with river views and a great atmosphere.
Siuslaw River Coffee Roasters, on Bay Street with a river deck, almost underneath the bridge, has friendly staff, excellent pastries, and a wide-ranging selection of coffee. 
Beachcomber Pub - nice beer selection and decent pub grub, gets going with locals on Saturday nights. (Bay Street, in Old Town)
Drive, cycle or hike down the scenic Oregon coast. Hike on the beaches, cycle on the Oregon Coastal Cycle Route, and drive on US 101. Hikers and cyclists are advised to proceed southwards in summer, when strong, cold north winds prevail.