Eisenach is well connected by Deutsche Bahn (DB) trains, from RB regional trains to IC and ICE trains. There are trains to the Frankfurt International Airport's Fernbahnhof, every two hours.
The town is walkable, and it is a brisk 30 minute hike to the Wartburg Castle up a hill. All other attractions, such as the Bachhaus, Lutherhaus and the churches, are within 10 minutes from the station.
On Deutsche Bahn, the other two main attractions of Thüringia, Erfurt and Weimar are within easy reach, with frequent and direct trains.