Il territorio dello stato è diviso in 88 contee, raggruppabili, grosso modo nelle seguenti regioni:
Mid-Ohio - una terra piatta a vocazione agricola posta intorno Columbus, capitale amministrativa dell'Ohio.
Nord Est (Ohio) (NEO), la regione della "Grande Cleveland" - rolling wooded foothills from the Allegheny Mountain range subside as they approach Lake Erie (definition of NEO includes 13 counties and 4.5 million people).
Northwest Ohio - flat agricultural land surrounding Toledo and stretching into Indiana to the west and Michigan to the north.
Southeast Ohio - very hilly, coal-mining country in the foothills of the Appalachian Mountains, rolling into Pennsylvania and West Virginia and including the Wayne National Forest.
Located north of Sandusky (between Cleveland and Toledo), a group of picturesque and festive islands in Lake Erie are accessible via ferry. In addition to several Ohio State Parks] located on the islands, there is plenty to do including wineries, restaurants, bars, marinas and beaches.
Along the southern shore of Lake Erie are a large number of public beaches. The largest natural sand beach in Ohio, Headlands Beach State Park, is located east of Cleveland, in Mentor. Cleveland Lakefront State Park also includes a large beach at its Edgewater Park, just west of downtown Cleveland. Many other beaches are available throughout Northern Ohio, including Huntington Beach, Euclid Beach and Fairport Harbor.
Lake Erie Circle Tour. Once you've had enough of the amusement parks and fishing venues, just follow the shoreline via the Lake Erie Circle Tour. The drive (or boat ride) takes you through the Working Waterfronts around Buffalo NY, Cleveland OH, Detroit MI, Erie PA, Toledo, OH, and southern Ontario is intermingled with beautiful preservations of flora and fauna as well as the history of North America's first westward expansion, the Old Northwest Territory.