The only practical way of entering Wiseman is via the Dalton Highway. Wiseman can be accessed by taking the highway to Mile 188 and taking a road to the west leading over the Koyukuk RIver.
There is no airstrip at Wiseman. The nearest airstrip is at Coldfoot, which lies 13 miles to the south. There are no car rentals in Coldfoot, nor regular transportation along the Dalton. Visitors who fly into Coldfoot will have to hitchhike with one of the many vehicles which travel along the highway.
For the adventurous, one can enter Wiseman via dog sled, although there is no such regular service with any other town in the region.
As the town is very small, the only practical means of getting around is by foot. In winter months, extreme cold can make walking deadly if not dressed appropriately.
The town contains numerous historic buildings.
There are no restaurants or groceries in Wiseman. Anyone visiting must supply their own food and drink.
There are no places in Wiseman to purchase alcohol. Drinking is not recommended as being intoxicated leads to bad judgement in a land where exposure and dangerous animals pose a grave danger to humans.