Limocar offers shuttle service from Montreal to Sherbrooke for 33$. Go2Go doesz not serve that area. Someday it might...
The STCS which is local transportation by bus offers either a one trip 'Jeton' that you have to buy at a tabagie or authorized dealers at 3.10$ that gives you one trip with all the transfers necessary. Also a more economical way to get from one place to the other is buying a day pass at 8.50$ that either gives the right for one or two adults with children (12years old or less) for a maximum of 6 passenger on one pass or one adult alone. Service for the bus ends at midnight if you need to get around after that use a taxi. It is not too expensive--about 30$ for one end to the other of the city but if you need one at night chances are you're in downtown. From there to the furthest hotel it would cost you 15$.
Taxi service Phone: 819-562-4717 also if you have a cell phone anywhere in quebec try *taxi they will patch you in the taxi service of your region cost locally is 99 cents.
Sherbrooke Museum of Fine Arts (Musee des Beaux Arts), 241 Dufferin, Tel: 819-821-2115 (fax: (819) 821-4003, email: firstname.lastname@example.org), . Tu-Su 1PM-5PM (summer 11AM-5PM); W 1PM-9PM. This art gallery is in the historic 19th-century Eastern Townships Bank building downtown. It displays both works of universal value and local flavor, focusing on the works of artists of the Eastern Townships, but also exhibiting other works. A dozen or so exhibitions are circulated through the lower two floors each year, while the third floor houses the museum’s permanent collection, featuring works by Frederick Simpson Coburn (1871-1960), originally from Melbourne in the Eastern Townships. $6, seniors/students $5.
Every summer there is the Fete du Lac festival at Parc Jacques-Cartier which features an international fireworks competition and many local artists.
Choux de Bruxelle, Phone: +1-819-564-1848. This restaurant is not a real Quebecois affair but somewhere you can have Moule et frite at less than 20$ and you bring your own wine. It is recognized by Sherbrookois to be the best value for your money and great food. You will need to make reservation in advance if you want to eat here during the weekend and during the month of November and December as many Christmas parties are celebrated there.
Louis Luncheonette, a local greasy-spoon. 3 locations in Sherbrooke. The fries are excellent. The meat is fresh. They also serve smoked-meat. Widely acknowledged as having the best poutine in Sherbooke; a regional dish that is must-have if you're visiting Quebec.
Stratos, another greasy-spoon, phone: +1-819-823-3333. Order poutine with frite bien cuit, sauce barbeque, sauce à part for maximum enjoyment. Pizzas are passable, and be sure to try their extra hot sauce suicide. However, the spare-ribs have an excellent sauce, heavy on the melases falvour.
Le Téléphone Rouge, 38 rue Wellington Sud, Phone: +1-819-566-9527, . Local and Quebecois musical performances Fridays and Saturdays, with live DJs on Thursdays. Caters to a musically-aware crowd. No cover when there are no shows, and on Thursdays. Between 5$-15$ on Fridays and Saturdays. Quebec beers only: 6$ for a pint.
Le Café du Palais, 184 ruelle Whiting (Wellington Nord), . Rockin' in Sherbrooke since 1979. During warmer weather it has a large terrace located in an alleyway with a stunning view of City Hall. Caters mostly to students and twenty-somethings. Live improv on Sundays.
Complexe le Living, 66 rue Meadow, . Club with four different rooms, each with a different setting. Hip Hop and Techno.