Porlamar is about a 30 minute drive from Margarita's Santiago Marino International Airport, via a fast highway.
Car rentals are available in Porlamar as well as in other parts of the island including at the airport and Playa El Yaque. Ensure that you thoroughly check the credentials of any rental agencies and ensure that they are licensed, have readily accessible office and an office contact number. Also ensure that you fully check the vehicle for any pre-existing damage including all lower body panels, the roof, and all window glass, before you sign the contract with any rental provider.
Learn Spanish, or pick up the first words necessary to get around while on the island.