From downtown one takes Forbes Avenue east which is a one-way street that leads directly to Oakland. There are frequent PAT buses as well as this is a heavily travelled route.
Although Oakland is essentially a location for schools and hospitals, there are many things to see and do there. Perhaps the most interesting for visitors is The Carnegie Library and Museums. There are three major sections in a single large building along Forbes Avenue:
There is a concentration of different colleges and universities in Oakland that is perhaps only rivalled in Cambridge, Massachusetts. These include, most notably, Carnegie Mellon University and the University of Pittsburgh, but there are many others, large and small, public and private.
Put some twenty thousand college students in a small urban area and you can be sure you won't go hungry. Or thirsty. If you've outgrown college food and college bars there are also a number of very good restaurants in the area.
There is always The O. The place for some of the best fries in Pittsburgh. All along Craig St. and Forbes are restaurants ranging from Chinese and middle eastern to Subway. Here is a small sample of what's there.
Essie's Original Hot Dog Shop 3901 Forbes Ave (412) 621-7388 Better known as "the O" or "the Dirty O". Originally opened across the street from Forbes Field. Cheap food. Extremely greasy. You can get giant piles of greasy french fries for cheap. It is a good place to go after drinking. Late hours. The place is filthy. You don't want to use the bathroom. It has a reputation for being dangerous, but there is always at least one cop there at all times. Most people go for the hot dogs, french fries, or pizza. If you are in Oakland, you should at least try the fries to say you have been there.
There is also a Five Guys Burgers and Primanti Brothers near campus, and of course larger chains like McDonald's, Wendys, and Panera Bread.
Bars and Pubs
Hemingway's 3911 Forbes Ave (412) 621-4100 Excellent food. $1 Beers, and food is half off from 9pm to 1 a.m. A good variety of items. Around $10 for a meal. The crowd is mostly frat boys.
Taiwan Cafe on Forbes has excellent, cheap Chinese food and there always seems to be a group of Chinese students inside enjoying a meal. They also have a huge selection of beer.
India Garden  on Atwood is often considered one of the best Indian restaurants in the city. Good atmosphere and food. They feature a lunch buffet and half off meals from 4-5pm and 10pm to midnight.
Star of India on Craig St., near the Carnegie Museums. It is across the street from an Indian grocery store.
Tamarind located at 257 N Craig St, further away from the campuses in an old Victorian house.
Mad Mex - Atwood Street = Great food. Food is half off from 11pm-1am. Mexican food. www.madmex.com The employees are mostly punk types while the crowd is usually yuppie.
Veracruz on Forbes is frequented by students for its inexpensive Mexican food, with a focus on beans.
The chains Chipotle and Q'Doba also have locations on Forbes.
Fuel & Fuddle Oakland Avenue = [] Good food. Vegetarian friendly. It has a hipster crowd. The prices are about $10 for a meal.
Hemingways - Forbes Avenue = $1 Miller Lites, microbrew selection, combined with the food, great place to drink. A lot of girls.
Gene's Place - Louisa Street = Really cheep drinks ($2.50 mixed, $2-3 22oz beers, $5.50 pitchers). No food. Some microbrews. Mostly guys looking to drink. If you are looking to drink cheap, here is the place.
Mad Mex - Atwood & Bates = Excellent beer selection (9 or so microbrews on tap, extensive bottle selection). The frozen margarita's are great. Expensive unless you come during a drink special (430-630 for happy hour, 9-11 for evening special). Great food if you like to eat while you drink.
Fuel & Fuddle - Oakland Avenue = http://www.fuelandfuddle.com/ The crowd is hipster. They have a large microbrew draft selection (12 or so) and an extremely extensive bottle selection.
Since this is a "college town", as well as a center of research and technology, there are numerous accommodations including most of the bigname chain hotels. In addition the area has very frequent bus connections to Downtown which is only a ten or fifteen minute ride to all the large downtown hotels.