Osnabrück is a typical mid-sized Lower Saxon town. It is home to around 160,000 people and surveys have proved them to be the most satisfied citizens in Germany. Osnabrück has seen its share of history and war. It was the ultimate city where the 30 Years War ended and over 2/3 of the city was then destroyed in World War II.
Flughafen Münster/Osnabrück FMO  is the best choice. The airport is quiet and efficient yet sufficient. There are flights from around Germany and a few European destinations on Air Berlin, Lufthansa, Cirrus Airlines, and Intersky and sorted public charters such as Sun Express and Hamburg International.
The shuttle bus X150  brings you to central Osnabrück in about 30 minutes for €9,50.
Many travelers choose to use other nearby airports for budget airlines and international connections. These include: Bremen for Ryanair, Dortmund for easyJet and Wizz Air, Düsseldorf for Air Berlin and Cologne or Hannover for germanwings.com. Consider the cost of ground transportation from these airports as train tickets can cost upwards of €70 if not pre-booked.
Osnabrück is well connected as it is a railway junction. Trains on the Amsterdam-Berlin route meet here with trains on the Hamburg-Cologne route. Die Bahn opereates most trains and connections for around Europe and Germany. The Dutch Nederlandse Spoorwegen (NS) sells discounted tickets to/from places like Amsterdam. Osnabrück is about 3 hours by express train from Amsterdam, Hamburg, Berlin and Cologne.
Other railways operate many of the local services but are always included in the DB search engine and tickets.
Osnabrück is also an Autobahn junction:
A33 from Bielefeld
International buses are normally slow local routes, especially the ones stopping in Osnabrück. They are normally only a good deal if traveling with tons of luggage or last minute, otherwise airlines are cheaper. The main bus station ZOB Osnabrück is located next to the train station.
The Mittellandkanal has a tangent running directly into Osnabrück (from Kilometer 30,4). There are not public boat services.
The city is most easily navigated by city/regional bus. The Stadwerke Osnabruck operates standard daytime as well as NachtBus (night) service on Friday and Saturday. They have an online trip planner as well as digital signs at many bus stops to inform you of the current predicted wait time.
Fare information is posted inside all bus shelters and most bus operators speak some English. Tickets are bought from the bus operator of from vending machines on the Neumarkt. Bus operators are obliged to give change if you over-pay in cash.
Many Osnabrückers choose to ride a bicycle as transportation since the compact size and good infastructure make it easy to get around. While utilizing the red-colored cycling lanes in Osnabrück one should exert caution. These lanes are often narrow, at street level, and/or shared with the city buses and taxis. Dangerous conditions lead to at least one bicyclist death a year in Osnabrück. Please use your best judgement and walk your bike on the sidewalk if you feel uncomfortable. Additionally there are many places where bicycles (and all cars) are forbidden in the city center. If you are riding on a street where there are no cars, be sure to double check that bicycles are not forbidden, because the police will stop you.
Osnabrück has several museums and a Culture Card / City Card  for museum lovers.
Among other (technical) schools Osnabück is home to a university. The university has several campuses dispersed throughout the city.
R&R Ice Cream , Eduard Pestel Strasse - English Friendly.
The favorite shopping area is the pedestrian zone Grosse Strasse (Big Street) in the city centre starting at the Neumarkt.
Osnabrück offers an array of foreign cuisine in addition to the "typical German food".
The best place to get a quick bite is at a Döner (Turkish Kebab) stand or restaurant. There are several local operations offering this type of food throughout the city.
There are many "Gasthäuser" and "Lokale," the local old school sit-down German food places.
The restaurant La Vie is very luxurious, if you have the money it's worth the visit.
You will never have to look far to find a drink. There are many youth and student oriented bars and clubs as well as bars and clubs for the more sophisticated. On a nice summer evening you will find many people congregate in the Schlossgarten (Palace Graden) to drink together.
Advena (next to train station) Westermann
Osnabrück is quite safe. There are break-ins and sometimes drunks getting lagered up, as well as rowdy, trouble making kids. Overall there are still very few violent crimes.
Still, the Neumarkt and the Rosenplatz should be avoided at night. The small Neumarkt-Undercrossing (the one without shops) should be avoided the whole day.
In some parts of Osnabrück, locals resent the British military bases in town and are reluctant to speak English unless you have made an attempt in German. In others, people may automatically recognise that you aren't German and may thus begin a conversation in English. Since British left Osnabrück in 2008 this may be diminishing.