To get into Middletown, or anywhere on Aquidneck Island, You can take one of three bridges: The Newport Bridge (Claiborne Pell Bridge), from Jamestown, Rhode Island, The Sakonnet River Bridge, from Tiverton, Rhode Island, or the Mount Hope Bridge, from Bristol, Rhode Island.
Rhode Island Public Transit Authority (RIPTA) offers (in season) daily trolley/bus service to all major points of interest in Middletown.
- Newport Vineyards, 909 East Main Rd. (Rte. 138), Phone: +1 401-848-5161, .
- Norman Bird Sanctuary, 583 3rd Beach Rd., Phone: +1 401-846-2577, . Daily 9AM-5PM. A 300 acre sanctuary for deer, fox, over 300 species of birds. Marked nature trails of up to 1.1 mi each (no pets permitted on trails). Lovely coastal views. $4.
- Holiday Cinemas, West Main Road, Phone: +1 401-847-3456.
- Sachuest Town Beach,, Sachuset Point Road. Known as Second Beach to locals, this is the largest beach in this area. Here you can find great surf, fine sand, showers, and a concession stand. Seasonal parking passes are available in the beginning of the summer season.
- Third Beach, Third Beach Road. This beach is known for its calm surf, which is perfect for water sports and small children. There are no public bathrooms or concession stand offered at this beach, but parking is available.
- Flaherty Charters, Middletown, . Charter a fishing boat.
- Newport National Golf Club, 324 Mitchell's Lane, +1 401-848-9690, . 18 holes, par 72, 7,244 yards, rating: 74.4, slope: 138. Rated #1 in Rhode Island by Golf Digest and GolfWeek.
- Crumb Kruncher's (children’s clothes), 496 East Main Road, Phone: 401-842-0848.
- Deborah Winthrop - Fine Lingerie & Gifts, 510 East Main Road, Phone: 401-846-3999.
- Island Sports (sporting goods), 86 Aquidneck Avenue, Phone: 401-846-4421.
- Walrus & Carpenter Toy Store, 909 East Main Road, Phone: 401-849-0012.
- A Shade Above, 700 Aquidneck Avenue, Phone: 401-849-5664.
- Anthony's Seafood & Restaurant, 963 Aquidneck Avenue, Phone: 401-848-5058.
- Atlanta Bread Company, 288 East Main Road, Phone: 401-841-0654 Fax: 401-841-0653.
- Atlantic Beach Club, 53 Purgatory Road, Phone: 401-847-2750.
- Atlantic Grille, 91 Aquidneck Avenue, Phone: 401-849-4440.
- Becky's Real BBQ, 82 East Main Road, Phone: 401-841-9909.
- Custom House Coffee, 796 Aquidneck Avenue, Phone: 401-842-0008.
- Easton's Point Pub & Restaurant, 116 Aquidneck Avenue, Phone: 401-847-0001.
- Flo's Clam Shack & Raw Bar, 44 Wave Avenue, Phone: 401-847-8141.
- Glass Onion, 909 East Main Road, Phone: 401-848-5153.
- Frosty Freeze, 495 East Main Road, ☎ 401-846-1697. Frosty Freeze is a great place to grab a delicious Ice Cream treat. They are open from 1 April, through 30 September - a schedule they have stayed true to for the last 51 years. They have a wide variety of both soft serve and 'hard' serve ice cream - as well as shakes, sundaes, and anything else you might expect at an ice cream shop. They are located right off of East Main road, and have a small area with picnic tables to sit at. Get there early, because the line usually stretches around the side of the building on a summer night.
- The Dawg House, 687 West Main Road, ☎ 401-324-4089. Amazing spot to grab lunch, or dinner. Not only do they have out-of-this-world hot dogs, but they have a wide variety of other foods as well. There are chicken dishes, sandwiches, soups, etc. - as well as scrumptious deserts - including cannolis and cazzolis! They are reasonably priced, and the service is one of a kind - you feel like a part of their family when there.
- Del's Lemonade of Middletown, 729 West Main Road, . Del's lemonade has been around for some time. While all stores don't carry every flavor, Del's has 'on tap' Lemon, Watermelon, Cherry, Peach/Mango, Blueberry, Light Lemon, Grapefruit and Pomegranate lemonades. This is not regular lemonade, but closer to a 'slushy' - having the flavor mixed in with chopped up ice chunks (and often times pieces of actual lemon). They have trucks and carts that are located all over Aquidneck Island - where you can pick up a lemonade to cool off.
- Bay Willows Inn, 1225 Aquidneck Avenue (Route 138A), Phone: 401-847-8400.
- Best Western Atlantic Beach Hotel, 34 Wave Avenue, +1 401 847-5330, Fax: +1 401 847-8041, .
- Carriage House Inn, 93 Miantonomi Ave, Phone: 401-841-0018. 
- Hampton Inn & Suites, 317 West Main Road (Route 114), Phone: 401-848-6555.
- Howard Johnson Inn, 351 West Main Road (Route 114), Phone: 401-849-2000.
- Paradise Motel, 459 Aquidneck Avenue (Route 138A), Phone: 401-847-1500.
- Sandpiper Cottage, 985 East Main Road (Route 138), Phone: 401-847-9726.
- Sea View Inn, 240 Aquidneck Avenue (Route 138A), Phone: 401-324-6200.
- Sea Whale Motel, 150 Aquidneck Avenue (Route 138A), Phone: 401-846-7071.
- Residence Inn by Marriott, 325 West Main Rd, Phone: 401 845 2005, . All-suite hotel, 2 miles from downtown Newport, offers separate areas for sleeping, living, eating, and a fully equipped kitchen. Indoor swimming pool & whirlpool. Free hot breakfast buffet daily, social events M-Th, beer and wine bar, summer barbeques, and free internet.