To get into Middletown, or anywhere on Aquidneck Island, You can take one of three bridges: The Newport Bridge (Claiborne Pell Bridge), from Jamestown, Rhode Island, The Sakonnet River Bridge, from Tiverton, Rhode Island, or the Mount Hope Bridge, from Bristol, Rhode Island.
Rhode Island Public Transit Authority (RIPTA) offers (in season) daily trolley/bus service to all major points of interest in Middletown.
- Newport Vineyards, 909 East Main Rd. (Rte. 138), Phone: +1 401-848-5161, .
- Norman Bird Sanctuary, 583 3rd Beach Rd., Phone: +1 401-846-2577, . Daily 9AM-5PM. A 300 acre sanctuary for deer, fox, over 300 species of birds. Marked nature trails of up to 1.1 mi each (no pets permitted on trails). Lovely coastal views. $4.
- Holiday Cinemas, West Main Road, Phone: +1 401-847-3456.
- Crumb Kruncher's (children’s clothes), 496 East Main Road, Phone: 401-842-0848.
- Deborah Winthrop - Fine Lingerie & Gifts, 510 East Main Road, Phone: 401-846-3999.
- Island Sports (sporting goods), 86 Aquidneck Avenue, Phone: 401-846-4421.
- Walrus & Carpenter Toy Store, 909 East Main Road, Phone: 401-849-0012.
- A Shade Above, 700 Aquidneck Avenue, Phone: 401-849-5664.
- Anthony's Seafood & Restaurant, 963 Aquidneck Avenue, Phone: 401-848-5058.
- Atlanta Bread Company, 288 East Main Road, Phone: 401-841-0654 Fax: 401-841-0653.
- Atlantic Beach Club, 53 Purgatory Road, Phone: 401-847-2750.
- Atlantic Grille, 91 Aquidneck Avenue, Phone: 401-849-4440.
- Becky's Real BBQ, 82 East Main Road, Phone: 401-841-9909.
- Custom House Coffee, 796 Aquidneck Avenue, Phone: 401-842-0008.
- Easton's Point Pub & Restaurant, 116 Aquidneck Avenue, Phone: 401-847-0001.
- Flo's Clam Shack & Raw Bar, 44 Wave Avenue, Phone: 401-847-8141.
- Glass Onion, 909 East Main Road, Phone: 401-848-5153.
- Courtyard Newport Middletown, 9 Commerce Drive, +1 401 849-8000, Toll-free: +1 888 686-5067, Fax: +1 401 849-8313, .The Courtyard by Marriott Newport Middletown is the perfect hotel when visiting historic Newport Rhode Island. Our Newport hotel is in the heart of the Middletown area business district and just 3 miles from historic Newport, beaches, and tourist destinations.
- Bay Willows Inn, 1225 Aquidneck Avenue (Route 138A), Phone: 401-847-8400.
- Best Western Atlantic Beach Hotel, 34 Wave Avenue, +1 401 847-5330, Fax: +1 401 847-8041, .
- Carriage House Inn, 93 Miantonomi Ave, Phone: 401-841-0018. 
- Econo Lodge, 1359 West Main Road (Route 114), Phone: 401-849-2718. 
- Hampton Inn & Suites, 317 West Main Road (Route 114), Phone: 401-848-6555.
- Holiday Inn Express, 855 West Main Road, +1 401 848-7128, .
- Howard Johnson Inn, 351 West Main Road (Route 114), Phone: 401-849-2000.
- Paradise Motel, 459 Aquidneck Avenue (Route 138A), Phone: 401-847-1500.
- Sandpiper Cottage, 985 East Main Road (Route 138), Phone: 401-847-9726.
- Sea View Inn, 240 Aquidneck Avenue (Route 138A), Phone: 401-324-6200.
- Sea Whale Motel, 150 Aquidneck Avenue (Route 138A), Phone: 401-846-7071.
- Residence Inn by Marriott, 325 West Main Rd, Phone: 401 845 2005, . This all suite hotel, just 2 miles from downtown Newport, offers separate areas for sleeping, living, eating, and a fully equipped kitchen. Unwind in the indoor swimming pool & whirlpool. Free hot breakfast buffet daily, social events M-Th, beer and wine bar, summer barbeques, and complimentary high speed Internet access.