The main (and in terms of passenger traffic) airport in the region is Poznan airport Lawica, situated very close (7 km) from the city centre, offering connections to more than 20 destinations accross Europe, including e.g : London, Frankfurt, Munich, Dublin, Paris, Rome, Amsterdam, Stockholm, Malmo, Copenhagen, Barcelona, Edinburgh. If your region is not connected by plane with Poznan, you can try other airports in surrounding polish regions : to Wroclaw (Breslau), Bydgoszcz or even Warsaw, that has very good train connection with Poznan.
Up-to-date flight schedule at Poznan Lawica Airport.
Region has very good connections with most other polish regions as well as some cities abroad. Its main (what doesn't mean, that's the only one) rail junction is Poznan, offering many inter-city and international connections :
Berlin : 4 times a day BWE (Berlin-Warsaw-Express) train - travel time ca 3 hrs