There are no major public transportation links to Carlisle. The Greyhound bus stop closed sometime after 2000, and there has not been a train station in the city for many years. The closest public transportation is in Harrisburg. The Pennsylvania Turnpike (I-76) and I-81 pass through Carlisle.
The two main streets in Carlisle are Hanover and High Streets. These streets intersect in the middle of town, creating a nice square by the courthouse. Most of the buildings of interest in Carlisle are located along one of these two streets.
Hotel Carlisle and Embers Convention Center, 1700 Harrisburg Pike, Carlisle, PA 17013, 1-(800) 692-7315, . Has 267 guest rooms and suites with special business class rooms. Accommodations include heated indoor pool, saunas, hot tub, fitness center, game room, 24-hour business center, and high-speed internet access. Special onsite features of Embers restaurant and "Shooters" billiards room.
Residence Inn by Marriott – Carlisle (Carlisle, PA Hotel), 1 Hampton Court Carlisle, Pennsylvania 17013 (Exit 226 off Turnpike and Exit 52 off I 81.), ☎ 717-610-9050, . checkin: 3pm; checkout: 11am. Award Winning Hotel 2 years running
Hampton Inn – Carlisle (Carlisle, PA Hotel), 1164 Harrisburg Pike Carlisle, Pennsylvania 17013, ☎ 717-240-0200, .
Sleep Inn, 5 East Garland Drive, ☎ 5 East Garland Drive, . The Sleep Inn® hotel is located directly off Interstate 81, less than one mile from downtown Carlisle, the U.S. Army War College and Dickinson College. This Carlisle hotel is minutes from the Carlisle Fairgrounds, Pine Grove Furnace State Park and Williams Grove Speedway.