Panhandle-Plains Historical Museum, 2503 4th Avenue, 806 651 2244. The largest historical museum in the state host a wide range of artifacts covering Panhandle pre-history, American Indian life, the early pioneer era, and cowboy life on the ranches.
Buffalo Inn, 300 23rd St, 806 655 2124. An older hotel, but clean and inexpensive.
Holiday Inn Express, 2901 4th Ave, 806 655 4445. Better than most locations of the same chain. Clean rooms, microwave, a good complimentary breakfast.