Bayreuth is a festival city in Upper Franconia (Oberfranken) a region of Bavaria, Germany. It is best known for being home to the famous classical musician Richard Wagner and for hosting the Festspiele.
The Hauptbahnhof (main train station) is located approximately 1 km north of the city center, easily accessed by foot. Several buses also run from the train station to the central bus station in the town center (Lines 2, 3, 5, 8, 9, and 13).
The nearest airport with regular commercial service is located in Nuremberg.
The bus network around Bayreuth provides extensive coverage of the city and surrounding areas. The central bus station (Zentrale Omnibus Haltestelle, ZOH) is located one block north of Maximilianstrasse near the city hall (Rathaus). The bus plan and schedule can be found at the website for BVB-Bayreuth  (in German only).
Compared to larger cities, Bayreuth is relatively easy to tackle by car. The pedestrian-only area in the center of town is confined to a few streets, and parking garages are easy to find.
Drink some of the local wheat beer - Hefeweizen - it is perhaps the best sipping beer in the world.
When traveling in summer, make sure not to miss the beautiful Theta beergarden. It is located in the hills above Bayreuth and it's hard to get there. But even taking a taxi would be worth it. For active people it is possible to do a very nice hike here from the Festspielhaus