Arles is in Provence in the southeast of France. Remote, uneventful, but definitely no waste of time, Arles is absolutely steeped in Provençal culture. The museums are small, but have some interested artifacts. Unfortunately there are no Van Goghs to be found in the city, despite the fact that his residence in Arles was his most productive. Chico Bouchiki, co-founder of the gypsy kings, as well as the rest of the band, is from Arles. Take a lazy stroll along the Rhône, dip into a café and continue strolling.
SNCF Gare d'Arles.
There are several bus lines from towns all over the Bouches-du-Rhône from which you can reach Arles. You can always buy your passage from the conductor.
Take the Autoroute from Salon or yet another from Marseille, but give preference to the smaller routes and Alpilles towns like Fontvieille, Paradou, les baux, etc.
The Roman ampthitheatre (les Arènes d'Arles) was built in the first or second century B.C.E. houses Corridas at Easter and the Rice Festa in September. Throughout the summer there are various courses camarguaises.
The Market and definitely think about researching for expositions and other events of the sort.
Saucisson d'Arles (traditionally made with a bit of donkey meat), marinated olives from the market, Languedoc cheeses from the market, etc.
Plats: Gardianne de Boeuf, Daubes, Fougasse d'Arles (with duck confit inside)
For restos, check out the menus on side street restaurants.
There is an Auberge de Jeunesse (youth hostel) at 20, avenue Foch. It's within walking distance of the train station. Another favored alternative is sleeping in the streets. Place de la libération offers a hospitable sidewalk with a boulder dedicated to two American WWII pilots shot down over Arles under shelter of which you may sleep.
There are a few hotels apparently built within parts of former abbeys, such as Hôtel du Cloître by Saint Trophime. Also, there are tons of hôtels de tourisme.
Arles is centrally located. The town straddles Provence and the Languedoc. Profit from its positioning and enjoy the great nature that surrounds: the Camargue and beaches to the south, the Alpilles to the east, etc.