Scioto County is in Southwest Ohio. The county seat is Portsmouth. It is located on the banks of the Ohio River which separates it from Kentucky and West Virginia.
- Lake Vesuvius
- Shawnee State Park
SR 23-104 NS - SR 52 EW follows the Ohio River
- Ohio River
- Scioto River
- Little Scioto River
- Shawnee Resort & Conference Center,  4404 State Route 125, Portsmouth. Located in the 63,000-acre Shawnee forest, the Shawnee Resort & Conference Center offers a many vacation attractions and amenities, golfing along Ohio River, indoor or outdoor pool. 65 miles of adjacent hiking trails, ideal for avid hikers or photographers. A cedar and flagstone lodge with 50 rooms, 25 - 2 bedroom cottages, and the O-Hee-Yuh Restaurant.
- The Ohio River is best viewed on Route 2, through Kentucky and West Virginia.
- Jade East, 3556 Rhodes Ave, New Boston, OH, ☎ (740) 456-8078. 1100-2200. Excellent Chinese-American cuisine. All food is created by the chefs, egg rolls are hand rolled, soups are created from scratch. Always a good choice. $$. edit