Once the site of the most elegant residential buildings in São Paulo, República was seriously hit by an exodus from downtown which happened mostly on the 1970s and 80s. Nowdays, it has been renovated as the whole historical central area. The streets between Praça da República and Largo do Arouche make up the oldest gay hot spot in town. It looks decadent, but many individuals young and old cruise in the clubs, movie theaters, dark rooms, and bars from Ipiranga Avenue down to Largo do Arouche. Rua do Arouche, República Square and Vieira de Carvalho Avenue are also known as pick-up spots where a few male, muscled prostitutes line up for services to men and women. There are also many "noias," or adoslecent and adult homeless people who are addicted to glue-sniffing or crack. Hate crimes by neo-Nazi skinheads have been reported in the area, but it has been well policed ever since. An arts and crafts and precious stones and food fair is held on República Square every Saturday and Sunday. The Republica station of the yellow subway line is presently under construction. Traditional gourmet restaurants and show-bars such as O Gato que Ri, Galeto's, and Bar Brahma are located on Largo do Arouche, Vieira de Carvalho, and Avenida São João, respectively. Bar do Leo, a 1940s pub that serves lunches and appetizers daily, is located on Rua Aurora.
Edifício Itália, Avenida Ipiranga at Avenida São Luís. It was for years the highest in the city, with its 160 meters. There is a bar and a restaurant on the 41st floor, but for the best experience ask to visit the open-air walkway around the restaurant. You may be expected to buy a drink in the bar first; cover charge is R$15 and it's around R$8 for a bottle of beer.
Royal, Rua da Consolação, 222, tel. 11 3255-6413. Posh club.
Trash 80's, Alameda Ribeirão Preto, 258, tel. 11 3262-4881. For those who miss those years.
Ultradiesel, Rua Marquês de Itu, 284, tel. 11 3338-2493. Gay club. 
Santa Fe, Praça Dom José Gaspar, 42. til midnight/1am. A decent bar within walking distance of the República metro station, considerably more down to earth than Bar Brahma but larger and a lot less intimidating than the smaller 'locals only'-style bars in the area. Plenty of tables outside and live music on at least some evenings.R$8 approx for 600ml beer. edit
São Paulo Hostel, Rua Barão de Campinas, 94 (at junction with São Joao, Metrô República), ☎ (11) 33330844, . checkin: 2.00pm; checkout: 12.00pm. Located near the Praça República, this HI-affiliated hostel is housed in a seven-story building, with clean rooms and large bathrooms for each dorm room. Wi-fi is available only on the top floor, which also houses a bar open in the evenings (except Sundays). Security is tight, which also means check-in and check-out times are tightly enforced.Non-members/members dorms R$41/33; singles R$69/57; doubles R$88/76; triples R$106/94. edit
Bourbon São Paulo, Avenida Dr. Vieira de Carvalho, 99, tel. 11' 3337-2000. 
Formule 1, Avenida São João, 1.140, tel. 11 6878-6400. 
Novotel Jaraguá São Paulo, Rua Martins Fontes, 71, tel. 11 2802-7000.