Quincy is served by Amtrak which comes into the Quincy Amtrak Station (QCY) at North 30th Street and Wisman Lane. Amtrak has two trains daily, originating in Chicago and terminating in Quincy. As of 12/2011, the trains depart Chicago at 7:35 AM and 5:55 PM and take approximately 4.5 hours.
If coming from St. Louis, you can take I-70 west towards Kansas City. At exit 210B, take the ramp right for US-61 North towards Hannibal. Stay on US-61, and in Hannibal, take the ramp right for I-72 East / Mark Twain Avenue East towards Springfield IL. / Downtown Hannibal. At exit 4B, take ramp left for I-172 North towards Quincy. Get off at exit 14, Broadway St., to get to the center of town. This trip takes roughly two and a half hours with traffic.
If arriving from Chicago, take I-55 / Stevenson Expressway towards St. Louis. At Springfield, keep right and stay on I-72 West. Keep straight onto I-172 North. This trip takes about four and a half hours with traffic.
Quincy has four major historical districts. The Quincy Historic Business District displays a wide variety of architectural styles and shows the wealth of the years 1850-1930 when Quincy was the most important river town in Illinois. Quincy’s East End Historic District contains every formal style of architecture found in the Midwest from 1830-1930. This East End area has a collection of Italianate, Greek Revival, Romanesque, Queen Anne and Prairie designs. Quincy’s South End Historic District was the home of Quincy’s German population. The sturdy homes, some ornate and others very simple, stand as reminders of Quincy’s German heritage. The fourth major historical area is Quincy’s North End, containing a collection of Italianate, Queen Anne and Renaissance Revival designs found in the Midwest from 1858-1930.
Governor John Wood Mansion, 425 S. 12th St., ☎ 217-222-1835, . M-F, 10AM-2PM. A Greek Revival mansion built in 1835.edit
Villa Kathrine, 532 Gardner Expressway, ☎ 217-214-3700, . M-F, 8:30AM-4:30PM. A Moorish-style castle on the bluffs of the Mississippi.edit
Granite Bank Gallery, 428 Maine, ☎ 217-228-2354, . One of Quincy's architectural gems, this spot is definitely worth a stop. The bank interiors have been preserved, right down to the massive safes. A coffee shop (Washington Perk) offers beverages, pastries, and sandwiches, and is a great place to hang out and relax (free Wifi, too). The gift shops offer mostly overpriced knick-knacks. Fun to browse, but keep your wallet closed.edit
Dr. Richard Eells House, 415 Jersey, ☎ 217-223-1800. Take a look at this documented Underground Railroad station.edit
Gardner Museum of Architecture & Design, 332 Maine St., ☎ 217-224-6873, . Be sure to visit the second floor stained glass gallery. The museum houses a collection of stained glass masterpieces salvaged from area churches.edit
Quincy Museum, 1601 Maine, ☎ 217-224-7669, . Tu-Su, 1PM-5PM. The corner of Maine and 16th streets, where the museum lies, once made the cover of National Geographic as one of the ten most architecturally significant corners in the United States.edit
All Wars Museum, 1707 North 12th Street (Illinois Veterans Home), ☎ 217-222-8641, . edit
18th and Maine Streets. Described as one of the top ten architecturally significant intersections in the U.S. by "National Geographic", this spot in one of Quincy's historic districts showcases four distinctive residential architecture styles. A walk through the surrounding neighborhood provides additional examples of late 19th and early 20th century architecture.Free. edit
Woodland Cemetery, 1020 South Fifth Street, ☎ (217) 222-2412. Created in 1857, Woodland Cemetery boasts magnificent views of the Mississippi River, mature trees and landscaping, and ornate grave markers and mausoleums. The cemetery is listed on the National Register of Historic Places, and contains the graves of many early Quincy and Illinois civic and business leaders.Free. edit
Downtown Quincy is where many locally-owned restaurants are. Most of the restaurant chains have a location on Broadway Street, the main drag that cuts straight through the middle of the city.
Gem City Pizzeria, 1801 State Street, ☎ 217-228-0550, . 4 p.m. - Midnight. A Quincy institution that has been around for decades, Gem City Pizzeria is a favorite of the locals. In addition to pizza and other Italian dishes, the menu also offers Mexican specialties. If you go on the weekend, be prepared to wait for a table. Carry-out and delivery are also offered, however.edit
Maid-Rite, 507 North Twelth Street, ☎ 217-222-7527, . Come to this local landmark to taste one of their unique loose meat ground beef sandwiches, a.k.a. Maid-Rites. This is the very first Maid-Rite in the franchise, and it is a great place for a cheap meal.$2-$9. edit
The Pier Restaurant, 401 Bayview Dr., ☎ 217-221-0020, . The name says it all. The building juts out into the Mississippi River, and provides great views of the Bayview Bridge and the river itself.$7-$29. edit
Tiramisu´, 137 North Third Street, ☎ 217-222-9560, . M-F 11AM-2PM, M-Sa 4:30PM-close. A great place to get authentic Italian cuisine at reasonable prices. $7-$17 (The most reasonable prices are during lunch hours). edit
Jorge the Crook's, 111 Hampshire, ☎ 217-224-9811, . Here they serve upscale American cuisine. This is the most expensive restaurant in town. Don't go here if you're short on cash.$6-$48. edit
Best Buffet, 5325 Oak St, ☎ 217-228-8883. M-Sa 11AM-3:30PM, M-Th 3:30PM-9:30PM, F-Sa 3:30PM-10:30PM, All day Su. The best Chinese buffet in town.edit
18 Wheeler Restaurant, 6723 Highway 6 (Go west on Broadway across the Mississippi River. Stay on US-24 West for about 7 miles. Get off at the ramp for MO-6 West toward Edina.), ☎ 573-769-2848, . Open 24 hours. This truck stop about 8 miles west of Quincy in Taylor, Missouri has the largest menu in the area. It specializes in massive breakfasts for truckers. Bring an appetite.$4-$15. edit
For those who want (or have) to make their own food, Quincy has plenty of grocery stores to choose from.
On the way out, you can follow the Great River Road north of Quincy towards Nauvoo, Illinois, and visit the sights there. Alternatively, you can drive south to Hannibal, Missouri, and see the Mark Twain sights
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