The Pioneer Valley is the region around the Connecticut River valley in Western Massachusetts. It is a very diverse travel destination, featuring urban, college town, and natural areas nearby.Its largest city is Springfield.
The three counties of the Pioneer Valley from north to south:
 The Connecticut River Valley
The valley is approximately 20 mi wide at the Connecticut state line but narrows northward. It holds much of New England's best farmland and thus was settled early in New England's colonial history. Since then, the farms have been encroached on by urban and suburban development, but many still exist. The Connecticut River Valley is mostly urban in the Knowledge Corridor region surrounding the cities of Springfield and Hartford (the two of which lie only 24 mi apart). The northern end of the Knowledge Corridor by Northampton and Amherst is a mix of urban and rural, featuring several prominent college towns. The northernmost section of the valley is rural, with many opportunities for outdoor activities.
The Connecticut River Valley's fine farmland and abundant water-power made the it Industrial Revolution's version of "Silicon Valley." Many industrial innovations took place at the Springfield Armory, including the discovery of interchangeable parts. America's first gasoline-powered car, motorcycle, and fire engine were all produced in Springfield. Holyoke became America's center of the paper industry. Industrialization encouraged growth of a string of cities from Northampton in the north to New Haven, Connecticut, in the south. From the early 1800s until the 1960s, the Connecticut River Valley was one of the most prosperous regions in the United States. Today this region is known as the Knowledge Corridor because of its numerous, prestigious universities and colleges.
The Connecticut River Valley remains one of the United States' major centers of higher education. Several of the United States' most prominent universities and colleges are located in the valley, including Amherst College, Smith College, and Mount Holyoke College. Mount Holyoke College was the first women's college founded in the United States. There are 14 colleges and universities located in the 20 mi8 from Springfield to Amherst.
 The Hill Towns or Hilltowns
A somewhat distinct and very rural subregion is the Hill Towns. This is the western part of the three counties, beyond the Connecticut River Valley. Higher elevation, later settlement, limited agricultural potential and cultural differences give the hilltowns a character similar to rural Vermont. Further west the hilltowns merge seamlessly into the Berkshire Hills, although tourism and second home development spreading out from the New York City metropolis have impacted the hilltowns less than Berkshire County.
 Eastern Uplands
Before the 20th century, highlands east of the Connecticut River developed along the same trajectory as the hilltowns to the west; however, development of Quabbin Reservoir during the 1930s created a large depopulated area in the northern 2/3 of this subregion. To the south, there have been modest population growth and development along the Massachusetts Turnpike and US Route 20.
 Get in
 By car
U.S. Interstate 91 connects the Pioneer Valley to Connecticut and Vermont. The Massachusetts Turnpike  connects it to Boston. Driving time from the Pioneer Valley to Boston is approximately two hours; to New York City, it is approximately three and a half hours.
 By plane
The closest major international airport serving the Pioneer Valley area is Bradley International Airport (BDL)  in Windsor Locks, Connecticut - 12 miles south of Springfield (and equidistant to Springfield's Knowledge Corridor sister city, Hartford, Connecticut.)
 By train
Rail service via Amtrak is available to Springfield as well as Amherst via the Vermonter. It is accessible by Amtrak's regional service, the Vermonter from the north and south, and the Lake Shore Limited from the east and west. Springfield will receive an exponential increase in rail traffic by 2014, so that schedules will change. In concert with the renovation of Springfield's grand, 1926 Union Station, (2011-2012) Springfield will become an intercity commuter rail hub both north and south, with the completion of the Springfield-New Haven high-speed intercity rail line from the south, (2014) and Amtrak's re-tooled Vermonter line, re-routed via the old Montrealer line in the Pioneer Valley following the Connecticut River (2012.) The Vermonter will make intercity stops in Springfield, Chicopee, Holyoke, Northampton, South Deerfield, Greenfield, and Brattleboro, Vermont instead of Amherst, making train travel in the Pioneer Valley much easier.
Springfield is also served east-west by Amtrak's "Lake Shore Limited" from Chicago to Boston and vice versa.
 By bus
Peter Pan Bus is headquartered in Springfield, and is one of the East Coast's major bus carriers. Greyhound/Peter Pan bus service is available to Springfield and many other Pioneer Valley cities.
 Get around
The Pioneer Valley Transit Authority (PVTA)  is the region's reliable and extensive public transport system. Its service extends from Springfield in the south to Amherst, 20 miles north of Springfield. Fares are $1.35, with a free "transfer" if one uses another PVTA vehicle within an hour of purchasing the original pass. On weekends, buses do not run all routes. Although the system is extensive for such a decentralized area, buses are somewhat infrequent and not all route run nights and weekends, especially outside of the school year (September - May).
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 Stay safe
In general, the Pioneer Valley is a very safe and accepting travel destination featuring an eclectic mix of urban, college town, and suburban settings - all of them relatively safe.
Springfield, the Pioneer Valley's largest city, which a decade ago ranked as high as 18th in the annual U.S. "City Crime Rankings", has seen a steep and steady decline in its crime recently - falling to 51st in the U.S. "City Crime Rankings" in 2010. Springfield is safe during the day, and nearly all of its well-travelled areas are safe and night - for example, the city's entertainment district and the area around the Basketball Hall of Fame are safe at all times. The neighborhoods where 80% of Springfield's crimes occur - Six Corners, Liberty Heights - are well off-the-beaten-path for visitors. That said, to be safe at night in Springfield, bring a partner with you.
The area around Six Flags New England across Springfield's South End Bridge in Agawam is safe day and night, as is the area around The Big E across Springfield's Memorial Bridge in West Springfield.
As of 2011, the City of Holyoke continues to make major strides in revitalizing. Holyoke is safe during the day; however, at night, if you intend on spending time downtown, stick to the commercial and entertainment blocks around High Street. The areas down the hill from High Street, South Holyoke and The Flats, remain dangerous. To be safe at night in Holyoke, bring a partner with you and stick to well-lit areas.
The City of Northampton is completely safe day and night, as is the college town of Amherst.
In general, the Pioneer Valley is very liberal socially and politically, and thus makes for a very accepting destination for lesbian, gay, bisexual, and transgendered (LGBT) travelers. This is especially true in the LGBT mecca of Northampton, and in Springfield's entertainment district, which features many establishments catering to LGBT consumers.
The following activities can pose safety risks in the Pioneer Valley:
 Get out