Hrodna – the center of the region and one of the eldest cities in Belarus. Hrodna is a home to the 12th century church, the old castle, and numerous remarkable buildings from late 17th – early 20th century.
Dziatlava – a small town with a nice catholic church from 17th century and a number of interesting secular buildings.
Iŭje – a town with an old catholic church and an unusual wooden mosque reminding of many centuries of presence of Tatar population.
Lida – an ancient town with a well-preserved castle from 14th century.
Mir – one of the most-known destinations in Belarus, the original castle from 16th century and the nice old town with 19th century buildings.
Navahrudak, also spelled Novogrudok or Nowogródek – an ancient town with the ruins of the 13th century castle and fine churches from 18th – 19th century. For tourists from Poland may be additionally interesting for its association with the poet Adam Mickiewicz, who was born nearby.
Slonim – a town with well-preserved churches and secular buildings from 18th – early 20th century.
Hieraniony – a village with a ruined castle an an old catholic church. In the 15th-16th century Gieraniony was the seat of the powerful Gasztołd (Gasztowt, Goštautas) family.
Haĺšany (Holszany) – a village with a ruined castle and a Baroque monastery, once a seat of a princely Holszanski family. Village of Golshany is enlisted in the Encyclopedia of Mysterious Places .
Hierviaty – a village with a magnificent neo-gothic church, one of the 3 tallest churches in the Republic of Belarus. Recently the Trinity Church of Gervyaty has been included into the list of 20 most important touist object 
Hniezna – a village with a well-preserved gothic church from 16th century.
Muravanka – a village with a fine example of the local type of fortifed gothic church. The 600-year old church of Birth of the Blessed Virgin Mary is a symbiosis of Gothic and Renaissance architecture and a candidate to be included in the UNESCO World Heritage List .
Synkavičy – a village that bosts the most fortified gothic church in the region and jne of the first Orthodox churches in Belarus .
Usieliub – a village with a catholic church originally built in gothic style in 15th century and repeatedly renovated, until returning to the gothic style during the gothic revival period.
Žyrovichy – a village that keeps a large monastery dating back to early 17th century. For already 500 years Uspensky monastery in Zhirovichy has been the bulwark of the Eastern Christianity on the Belarusian land 
Krevo – a small town with ruins of Krevo Castle dated back to 1338. In 1385 the castle became the place where the Krevo Union of the Grand Duchy of Lithuania and Poland was signed .