Car, or regular train service from Interlaken are the main options. Train journey time is a little above half an hour and usually cost 8-12 franks. Interlaken has connections to other major Swiss cities.
Charter/Tour buses, taxis, and car rentals are also possibilities. Mysterytours  offers some options, as does Fun-rental Interlaken. Only 30 minutes by scooter to Grindelwald from Interlaken.
In summer and early fall, is also possible to hike into Grindelwald from well-marked Bernese Oberland trails, with or without the assistance of gondolas / cable-cars.
Grindelwald has two train stations: Grindelwald and Grund. The Grindelwald station is in the center of town; the Grund station is in the valley floor, on the way to Kleine Scheidegg. Wengernalpbahn trains (painted yellow and green) to Kleine Scheidegg generally stop at both stations. Berner Oberland Bahn trains (in blue and yellow livery) from Interlaken via Zweilütschinen stop only at Grindelwald. If you plan to walk between these stations, be aware that the two stations are about 1 km apart, and separated by roughly 100 m of vertical elevation.
A local bus service  can get you to nearby destinations.
The gondola lift to Männlichen departs a few hundred meters west of Grund station. The gondola lift to First begins about ten minutes' walk east of Grindelwald station, while the cable car to Pfingstegg is about fifteen minutes' walk east of Grindelwald station.
There is an information centre in the village. There is also a local history museum.
Grindelwald is a ski resort in winter and famous for hiking in summer. Also a starting point for Eiger and Wetterhorn tails.
Swiss Army Knives
As anywhere in Switzerland you should buy a knife (or several as they make excellent gifts)
Most places have the same prices and a decent collection. But Vogts Corner on Hauptstrasse stands out because here all knives are on display for you to touch, fondle and try out. Another good thing is that they have both Wenger and Victorinox knives on display if you are having trouble to decide. You'll find it by Hans Passage near Coop.
Internet & Hotspots
Foto Grindelwald  is an Internet-Cafe in Grindelwald.