Many of the ideas in Frank Herbert's Dune series came to him during a trip to Florence to write a magazine article about a US Department of Agriculture project there.
Florence is also known as the site of the exploding whale, an incident when the Oregon State Highway Division tried to remove a beached whale by dynamite - with unintended results.
Florence Municipal Airport has general aviation services but no scheduled flights
Porter Stage Lines  run a twice-daily service from Ontario (Oregon) to Coos Bay, which calls at Florence. It connects in Eugene with Greyhound bus and Amtrak train services. Through ticketing is available.
The scenic Oregon coast route, US Highway 101, passes through Florence. The Eugene-Florence Highway, Oregon route 126, follows the Suislaw River valley to dead-end on 101 at Florence.
Play golf at Sandpines Golf Links. A Rees Jones design and a true links course, Sandpines was voted "Best New Golf Course" by Golf Digest in 1993 and "4-1/2 Star Rated 'Places to Play in USA'," by Golf Digest for 2006 and 2007. Visit www.sandpines.com for more information, or call 800-917-GOLF (4653). A truly unique course in Oregon.
Restaurants are clustered in the old town, especially in Bay Street; those on the river side of the street usually have decks over the river.
The Waterfront Depot in Bay Street, with a river deck, is the restaurant most strongly recommended by locals, and reservation is advised. It is housed in the former railroad depot from Mapleton, a few miles up the Suislaw River. The Italian restaurant (1285 Resto Bar) opposite the Waterfront Depot is under the same ownership and is also strongly recommended by locals.
Mo's - Fish & Clamchowder restaurant in Florence's old town. Great view of the Siuslaw river and one of the best clam chowders to be found on the Oregon coast. This local chain of restaurant's was started in Newport, Oregon.
Old Town Florence packs many more great restaurants, many with river views and a great atmosphere.
Siuslaw River Coffee Roasters, on Bay Street with a river deck, almost underneath the bridge, has friendly staff, excellent pastries, and a wide-ranging selection of coffee. 
Drive, cycle or hike down the scenic Oregon coast. Hike on the beaches, cycle on the Oregon Coastal Cycle Route, and drive on US 101. Hikers and cyclists are advised to proceed southwards in summer, when strong, cold north winds prevail.