Extremadura  is a region of Spain.
La Ruta de Isabel La Católica
If you plan on visiting the town of Guadalupe, in the Sierra de Guadalupe, you might consider hiking La Ruta de Isabel La Católica. This 17km trail starts in the nearby village of Cañamero, which can be reached by bus. The well marked trail winds it's way past beautiful lakes and stunning hills before descending into Guadalupe. The hike takes about half a day.