There is an air-con bus serving Phnom Penh to Can Tho, Vietnam. The bus leaves P. Penh daily at 6.00am.
The bus uses the Phnom Den/Tien Binh Border crossing and will pass Chau Doc enroute to Can Tho. The fare is US14.00 only. It takes about 4+ hours to Chau Doc and another 2+ hours to Can Tho. The booking office is Bus Express Travel Cambodia at #09 DEo, Street 230, Phsar Deumkor, Phnom Penh. Telephone: 855 997 90443; 855 972 119 339. One has to pay the same fare even though one intend to stop at Chau Doc.
A stroll along the riverside will be well worth it. You will bump into many young people eager (but a bit shy) to engage you in conversation. It can be very rewarding after a morning spent haggling in the colourful markets.
A traditional massage with suction cups is a great way to relax and unwind before returning to HCMC or taking one of the riverboats to Phnom Penh
The Victoria Chau Doc Hotel, 32 Le Loi, will let you use their pool by the river for $5.00 per person. Your receipt will give you access vor the entire day so you can go for a refreshing dip, go somewhere cheaper for dinner and come back to watch the action onthe river while the sun goes down.
Thanh Tinh, 13 Quang Trung (close to the indoor market). 6AM-9PM. A nice and clean local restaurant that serves vegan food. Friendly and English speaking staff. They can also prepare take-away meals (handy for the journey on the slow boat to Cambodia). Be aware, they charged 95,000 VND for a 'COM PHAN', almost three times expensive than usual price. (March, 2011)25,000-40,000. edit
Bay Bong, 22 Duong Thuong Dang Le (With the indoor market on your right hand side, continue until you can only go left or right. Go right there and you'll eventually see it on your left.), ☎ (076) 867 271. Good food here with a very long menu. Locals eat here as well. The atmosphere isn't particularly romantic, but still.25,000-55,000. edit
Hang Chau II Hotel, 10 Nguyen Van Thoai, ☎ 76.868891, 91.3970831 (email@example.com, fax: 76.865.140). Good budget option, within walking distance from the market and the river. It's a bit impersonal, with a lack of decorative touches throughout the building, but it also has a stately 1960's ambiance, and the rooms are big. Parking is available. It's a popular destination for tour groups, so check in early.Rooms with hot water and a/c cost about US$8. edit
Thuan Loi Hotel, 18 Tran Hung Dao St.. Has the best location out of the budget hotels, right on the river, but it's also a tour-group stop. Rooms have hot water and a/c.edit
Trung Nguyen, 86 Bach Dang. Great staff.Rooms are small but very clean, with hot water, a/c, and television, and cost about $10.. edit
MOTEL Number 6 Thanh Mai, 6 Phan Van Vang St, ☎ 076.3867622. For a budget place, the atomosphere is clean and relaxing. Potetional for bus station pick-up and Mekong slow boat/bus trip to Phnom Penh available for US$10 (as of Dec. 2011)Rooms with hot water and a/c cost about US$9, rooms with hot water and strong fans are only $6. edit
Vinh Phuoc Hotel, 12-14 Quang Trung, ☎ 866242, 562265 (firstname.lastname@example.org), . A great budget deal, this place is run by an amiable Brit who is an excellent source of local travel information. Free wifi at receptionUS$ 6-20. edit
MURRAY Guesthouse (Nha Nghi Thuyen Truong), 11-15 Truong Dinh (Right off Le Loi, 150m east past Cathedral), ☎ 84 76 3562108 (email@example.com). checkin: 11.00; checkout: 12.00. Boutique family-managed accommodation that sets the benchmark to international standards: 10 rooms, a.c., guest lounge with private bar and pool/snooker table, travel advice, free wifi and breakfast. From $25. edit
Victoria Chau Doc Hotel, 32 Le Loi, ☎ 76.865010 (fax: 76.865020), . A luxury hotel where you'd least expect to find one, with no amenity left behind. Features 92 rooms, 4 suites, and total incongruity with its surroundings. Transfers to Phnom Penh via private speedboat are available.Rooms from $99-$155, river view suites from $144-$220. edit
When arriving by boat, you may be met by a number of fairly aggressive cyclo drivers. If you do not require their services, you may be followed (in the hope that you will realise the error in your decision to walk or arrange alternative transport), and whilst this is unlikely to present any problems, it may be unnerving. If you are waiting for alternative transport, you may wish to do so in a bar, rather than on the street. Beware of the usual warnings about scams.
Can Tho is a popular next stop for travelers on a tour of the Mekong Delta. It can be reached by boat: the daily cruise leaves at 9.00 AM and costs 700.000 VND (jan/13)
Ho Chi Minh City. Phuong Trang bus company (phone 0.76 3.565.888) make the connection for 125,000 Dong 6 times a day between 8.45am to 12.15am.
Phnom Penh is another popular destination. Many travelers stay for one night in Chau Doc and go the next day to Cambodia. Several boats are available, from slow boats to fast boats. A journey on a slow boat can take up to 10h to Phnom Pehn, and the quality of the boats is not always the best (extremely noisy engine, heavy vibrations, a lot of sun and no toilet can make a 10h trip really long). I costs VND 420.000 (feb/13). Most likely, some of the tour operators will tell you, that they have to get the visa for you and that it is now more expensive and other lies (such as the border crossing closes soon and they will get there faster with your passport using a motorbike, etc..) but this is not true and you can ignore them. Try not to take to many dongs with you, because the exchange rate you get is not very fair. There is no ATM, so bring enough dollars with you. At the border, there is a small restaurant, but it is comparably expensive. You can get take-away meals and a bottle of water from restaurants in Chau Doc if you plan ahead.